Vesicle-Based Sensors for Extracellular Potassium Detection
Anna Davis, Biomedical Engineering, 2021
Potassium ions (K+) are one of the most abundant ions in intracellular fluid, affecting a wide variety of cellular processes in living organisms. In humans, irregularities in extracellular K+ levels contribute to pathologies including cardiovascular disease, immunological diseases, and some cancers. Despite the role of K+ ions, the detection, quantification, and monitoring of K+ remains difficult. While fluorescent indicators exist that can provide a fast, easy readout for K+ concentration, they are often nonspecific, particularly... View the presentation.